Karen Liby Selected Research

2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid methyl amide

4/2009

Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.

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Karen Liby Research Topics

Disease

14	Neoplasms (Cancer) 01/2013 - 08/2002
8	Breast Neoplasms (Breast Cancer) 01/2013 - 01/2003
8	Carcinogenesis 05/2012 - 08/2002
5	Lung Neoplasms (Lung Cancer) 12/2009 - 07/2006
3	Inflammation (Inflammations) 04/2009 - 07/2006
2	Carcinoma (Carcinomatosis) 12/2009 - 03/2007
2	Leukemia 08/2008 - 06/2006
1	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2010
1	Huntington Disease (Huntington's Disease) 07/2010
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2010
1	Adenocarcinoma of Lung 12/2009
1	Retinal Degeneration 11/2009
1	Macular Degeneration (Age-Related Maculopathy) 11/2009
1	Amyloid Plaque 04/2009
1	Alzheimer Disease (Alzheimer's Disease) 04/2009
1	Osteosarcoma (Osteogenic Sarcoma) 05/2008
1	Neuroblastoma 05/2008
1	Hyperplasia 05/2008
1	Rhabdomyosarcoma 05/2008
1	Ewing Sarcoma (Sarcoma, Ewing) 05/2008
1	Adenocarcinoma 03/2007
1	Myeloid Leukemia (Leukemia, Myelocytic) 06/2006
1	Neoplasm Metastasis (Metastasis) 01/2003

Drug/Important Bio-Agent (IBA)

11	TriterpenesIBA 05/2012 - 06/2006
6	AcidsIBA 05/2012 - 06/2006
6	bardoxoloneIBA 07/2010 - 06/2006
5	Estrogen ReceptorsIBA 05/2012 - 05/2004
5	bardoxolone methylIBA 05/2012 - 03/2007
5	LG 100268IBA 12/2009 - 05/2004
4	CarcinogensIBA 12/2009 - 03/2007
4	vinyl carbamateIBA 12/2009 - 03/2007
3	EstersIBA 05/2012 - 03/2007
3	2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid ethyl amideIBA 07/2010 - 03/2007
3	AmidesIBA 07/2010 - 03/2007
3	Proteins (Proteins, Gene)FDA Link 12/2009 - 07/2007
2	Pharmaceutical PreparationsIBA 05/2012 - 05/2004
2	ErbB Receptors (EGF Receptor)IBA 05/2012 - 05/2008
2	AGN 194204IBA 12/2009 - 10/2007
2	AntioxidantsIBA 11/2009 - 04/2009
2	EnzymesIBA 08/2008 - 07/2007
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 08/2008 - 07/2007
2	Transcription Factors (Transcription Factor)IBA 03/2007 - 07/2006
2	LY 353381 (LY353381)IBA 10/2006 - 05/2004
2	Selective Estrogen Receptor Modulators (SERM)IBA 10/2006 - 05/2004
2	ProlactinIBA 05/2003 - 08/2002
1	LDN 193189IBA 01/2013
1	ChemokinesIBA 05/2012
1	Oncogene Proteins (Oncogene Protein)IBA 05/2012
1	Cyclin D1IBA 05/2012
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2012
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2010
1	Synthetic DrugsIBA 12/2009
1	oleananeIBA 12/2009
1	(2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oic acid) trifluoroethylamideIBA 11/2009
1	2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid methyl amideIBA 04/2009
1	Amyloid (Amyloid Fibrils)IBA 04/2009
1	Aligeron (AS 2)IBA 04/2009
1	AflatoxinsIBA 08/2008
1	TBE 31IBA 08/2008
1	Interleukin-6 (Interleukin 6)IBA 07/2008
1	bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA 05/2008
1	Retinoid X Receptors (Retinoid X Receptor)IBA 05/2008
1	Biological ProductsIBA 05/2008
1	LigandsIBA 05/2008
1	LG 268IBA 05/2008
1	2-cyano-3,12-dioxoolean-1,9-dien-28-oic acidIBA 05/2008
1	CaspasesIBA 05/2008
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 05/2008
1	Betulinic AcidIBA 07/2007
1	Heme Oxygenase-1IBA 03/2007
1	Nitric Oxide Synthase (NO Synthase)IBA 03/2007
1	Drug CombinationsIBA 10/2006
1	ritetroniumIBA 10/2006
1	1- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA 06/2006
1	Differentiation AntigensIBA 06/2006
1	Carboxylesterase (Hydrolase S)IBA 06/2006
1	Transforming Growth Factor beta (TGF-beta)IBA 05/2004
1	Hormones (Hormone)IBA 05/2003
1	Collagen Type XVIII (Type XVIII Collagen)IBA 01/2003
1	EndostatinsIBA 01/2003
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2002

Therapy/Procedure

3	Therapeutics 11/2009 - 08/2002
1	Drug Therapy (Chemotherapy) 08/2008
1	Chemoprevention 08/2008
1	Aftercare (After-Treatment) 05/2008